Vaccines, like any other pharmaceutical product, may cause allergic reactions, from mild to severe, in people with very high sensitivity to the active substance or to any of the ingredients contained in the vaccine. The safety data based on clinical trials has not shown any increased risk of allergic reaction, although given the limited number of vaccines administered so far, very rare) allergic reactions (which means fewer than 1 per 10,000 people vaccinated) may still occur.
As a general rule with all injectable vaccines, appropriate medical treatment and supervision should always be readily available, and a post-vaccination observation period of at least 15-20 minutes should be guaranteed. The persons with a history of an immediate allergic reaction of any severity to a vaccine or injectable therapy and persons with a history of anaphylaxis due to any cause should be observed for 30 minutes after vaccination.
- COVID-19 vaccines may cause an allergic reaction, like any other vaccine or drug.
- Recipients should be observed for 15-30 minutes following vaccination.