An additional dose of a vaccine is recommended for immunocompromised people for all COVID-19 vaccines with WHO Emergency Use Listing.

Individuals with immunocompromising conditions and those receiving immunosuppressive therapy often do not develop an adequate immune response to a standard primary series of COVID-19 vaccination. Therefore in these cases an additional dose in the primary series is needed to optimize or enhance the immune response and thereby increase effectiveness against disease.

On the basis of available evidence, the additional dose in an extended primary series should be given at least 1 month and within 3 months after the primary series in order to increase protection for ICPs. If more than 3 months have elapsed since the last dose in the standard primary series, the additional dose in an extended primary series should be given at the earliest opportunity.