Every fetus in early pregnancy starts out with a 3-5% chance of having a birth defect. This is called the background risk. The available studies have not found an increased chance of birth defects when a pregnant woman receives a COVID-19 mRNA vaccine during the first trimester. Growing evidence shows that COVID-19 vaccination during pregnancy can benefit both the mother and her child. It also shows that COVID-19 vaccination during pregnancy does not harm the fetus, and that vaccination prior to pregnancy does not reduce female fertility. Vaccination is protective and much safer than COVID-19 infection.