In general, persons with a severe allergic reaction (anaphylaxis) to the first dose should not receive additional doses of the same vaccine.
As a small number of anaphylactic reactions have also been reported in vaccinees without a history of severe allergic reactions, WHO recommends that COVID-19 vaccines should be administered only in settings where anaphylaxis can be treated. Until more data and insights are available with regard to severe allergic reactions to COVID-19 vaccination, all vaccinees should be observed for at least 15 minutes after vaccination.
