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General questions

COVID-19 vaccines and vaccination explained – Introduction

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4/14/2021

Hello and welcome to “COVID-19 vaccines and vaccination explained”, an information site on COVID-19 vaccines and vaccination, developed by the WHO Collaborating Centre for Vaccine Safety of Santiago de Compostela.

Vaccines against COVID-19 are already available, and they constitute the most valuable tool against this pandemic. Together with the other control measures and individual responsibility to prevent transmission, they will allow us to progressively recover our normal life.

This website is here to facilitate our collective understanding of COVID-19 vaccines and vaccination, their development, characteristics, clinical use or any other relevant issue. We pledge to share reliable and up-to-date information, and to respond to any questions that might arise.

All the answers are provided in the form of short videos, podcasts and text, in different languages, either as originally recorded or with subtitles. Feel free to download, reuse or disseminate all of these materials at your convenience.

Our answers are all based on the latest scientific evidence and current recommendations from WHO. We are all aware that knowledge is evolving very rapidly, and that new questions will continue to arise. We will do our best to keep this platform up to date.

Feel free to send us any questions related to COVID-19 vaccines and vaccination, as well as any suggestion that may help us make this resource more useful to you.

We hope this tool is of your interest and that it will contribute to a better understanding of the role, characteristics and possibilities of COVID-19 vaccines and vaccination.

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COVID-19 vaccines and vaccination explained – Introduction

2:39

Vaccines protect against severe COVID-19 disease.

1:22

Why are some vaccinated people also hospitalized with COVID-19?

0:58

How could vaccines be developed at record speed while still maintaining quality and safety?

2:29

What are clinical trials and are they enough to prove a vaccine is safe?

3:21

How do mRNA vaccines, like Pfizer-BioNTech and Moderna COVID-19 vaccines, work?

2:13

How do vector vaccines work?

3:34

How should we respond to claims that the mRNA vaccines could cause a genetic change and that we will see this in the coming decades?

2:36

How do inactivated vaccines work?

4:41

How do protein-based vaccines work?

3:44

How do I know which COVID-19 vaccine to choose or recommend?

1:32

What tests or examinations should people get before COVID-19 vaccination?

0:57

Can a new variant of the SARS-CoV-2 virus cause more severe disease?

1:40

Why should older adults get vaccinated?

1:33

Omicron is generally less severe than previous variants – does it still make sense to vaccinate children?

2:57

Should children aged 5-11 get a booster dose?

1:29

If COVID-19 becomes endemic will vaccination still be needed?

1:01

Why is it necessary to stay in the healthcare facility 15-30 minutes following COVID-19 vaccination?

1:42

Is it possible to catch COVID-19 during an immunization visit to a healthcare facility?

1:12

What are the so-called COVID-19 bivalent booster vaccines?

5:07

What is the recommended use of updated bivalent COVID-19 booster vaccines?

2:15

How do the updated bivalent COVID-19 vaccines work?

1:52