One sees the opinions and the reactions to vaccination today, and one is startled to see that in the countries that should most appreciate vaccination – that is the developed high-income countries – the opposition to vaccination is highest. Not surprisingly, in countries, which are lower middle-income countries, vaccination is highly prized because people or rather children are still dying, and adults, for that matter, are still dying of vaccine preventable diseases. So what I see today, and by that I mean 2020-2021, is a paradox. The paradox is that we have never had such profound importance of vaccination since, maybe, the last couple of hundred years. We have this tremendous need for vaccination owing to COVID-19. And yet in some countries and, in particular, I would say, the United States, you have opposition to vaccination which is a paradox.